Cocorex® Cough Syrup Actions
Chlorpheniramine Maleate is an antihistamine which reduces allergic vasodilation and mucosal congestion. It provides relief in allergic conditions. Codeine Phosphate acts centrally and has a cough suppressant action. It reduces the intensity and frequency of bouts of coughing and is the reference compound with which other antitussives are compared. It also has a mild analgesic action.
Cocorex Cough Syrup is indicated for the relief of troublesome bouts of coughing, especially coughs that disturb sleep and cause pain. It is effective in dry unproductive coughs such as those which are associated with influenza, whooping cough, heavy smoking and allergies. Cocorex Cough Syrup is contraindicated in patients who are hypersensitive to any of its constituents.
Chlorpheniramine maleate, an H1-blocking antihistamine, relieves histamine-induced allergic edema of respiratory mucosa. Codeine phosphate, by its action on the cough center in the medulla, helps reduce excessive frequency and intensity of cough bouts, which allows the patient to rest or sleep.
Codeine and Chlorphaniramine may cause drowsiness. Caution should be exercised when driving and operating machinery or appliances. Dependence on codeine occur but it isuncommon with antitussive use, because of the short duration of therapy and the small doses required. The following should not be administered concomitantly with Cocorex, antihypertensives with central nervous system depressant effects, sedatives tranquilizers, alcohol, MAO inhibitors and other CNS depressants. Cocorex should be used with caution in patients with a history of hypertension, heart disease, diabetes mellitus, hyperthyroidism, increased intra-ocular pressure, bronchial asthma and hepatic impairment.
Adverse effects occur rarely with the suggested dosage. Chlorpheniramine Maleate may cause drowsiness, dry mouth, blurred vision, weakness, nausea and headache. Codeine is generally well tolerated. Vomiting, constipation, dizziness, drowsiness, pruritus, sweating and agitation have been reported.
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Information for Health Care Professionals
*** Please consult local Prescribing Information for any product before use. This website is an international information resource for healthcare professionals with an interest in disease management. This website is not intended to replace the advice of a qualified healthcare professional. Above brand is a trademark of the Taj group of companies (Taj Pharmaceuticals Limited).
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